Figure 2.

PGE₂ metabolism by isolated choroid plexuses from lateral ventricles of 2-day-old rat brain. Data are expressed as mean ± SD of three different experiments, and represent the amount of radioactivity associated to each molecular species, relative to the initial radioactivity associated to PGE₂ (see method), after either 5 or 45 minutes of incubation. * and **: different from PGE₂ amount in incubation without choroidal tissue, p < 0.05 and 0.01, respectively, paired student's t-test. Abbreviations: KPGE₂: 15-keto-PGE₂, DHKPGE₂: 13,14-dihydro-15-keto-PGE₂, BCPGE₂: bicyclo-PGE₂.