Figure 1.

Radiochemical reverse phase HPLC analysis of PGE₂ metabolism by isolated choroid plexuses. Typical chromatograms are shown: a and b are UV profiles of RH buffer (a) and RH buffer supplemented with PGE₂ and its main potential metabolites (b); c and d are radiochemical chromatograms of RH medium incubated for 45 min in the absence (c) and presence (d) of lateral ventricle choroid plexuses from 2-day-old rats. In c and d the y axis represents radioactivity concentration (dpm/ml) in each collected fraction.