Figure 1.

Photographs and MR scans of unaffected H-Tx and hydrocephalic H-Tx rat pups at P10. Phenotype of H-Tx pups at P10: A, unaffected H-Tx pup and D, hydrocephalic pup. Note the enlarged domed head, usually evident by 3 days of age in D. Representative sagittal MR scans of unaffected H-Tx (B) and HC animal (E) showing enlargement of lateral ventricles, and normal sized cerebellum. Coronal T2-weighted slices confirm small lateral ventricles of unaffected H-Tx (C) and the large lateral ventricles in the HC pup (F).