Table 1

Characteristics and results for patients with Creutzfeldt-Jakob disease
Sex/age (years)
 Disease
duration1
(months)
 EEG
 MR
 Autopsy
 tTau
(ng/L)
 P-Tau4
(ng/L)
 tTau/P-
Tau
(ng/L)
 Aβ42
5 (ng/L)
 14-3-3
protein
Female/84
 2
 TSWC2
 NC8
 Denied
 7,090
 49
 173
 664
 Not done
Male/75
 6
 TSWC
 NC
 Denied
 13,830
 211*
 65
 385*
 Positive7
Male/62
 4
 GD6
 NC
 Not done
 12,910
 149*
 83
 372*
 Not done
Female/58
 22
 GD
 NC
 Denied
 1,880
 92*
 26
 623
 Positive7
Female/77
 3
 TSWC
 HSC9
 Positive3
 3120
 45
 69
 704
 Positive7
Female/67
 4
 TSWC
 HSC
 No result
 8532
 66
 129
 526*
 Positive7 0.96
Female/64
 Rapid
 TSWC
 HSC
 Positive biopsy 3
 14,060
 84*
 167
 562
 Positive7 3.68
Male/74
 2
 GD
 HSC
 Not done
 22,460
 82*
 274
 946
 2.42
Female/65
 >23
 TSWC
 HSC
 Not done
 1,343
 72
 193
 M
 0.30
Female/70
 15
 TSWC
 HSC
 Not done
 2,348
 93*
 25
 1051
 0.35
Female/61
 Rapid
 TSWC
 HSC
 No result
 11,038
 48
 230
 755
 1.75
Male/54
 5
 TSWC
 HSC
 No result
 71,900
 172*
 97
 1042
 Positive7 9.70

1The time from disease recognition to death, 2Three-phase sharp wave complexes, 3Positive for immunochemical examination of pathological prion protein, PrPSc, 4Values above the normal limit used in clinical practice marked with *, 5Values below the normal limit used in clinical practice marked with*, 6Generalized dysrythmia, 714-3-3 protein found positive in different laboratories outside Norway because some hospitals sent CSF samples for 14-3-3 protein analysis to laboratories outside Norway in parallel to sending samples to us. (Three patients both have semi quantitative results from us and a qualitative, positive result, from a foreign laboratory). 8NC, non-specific changes. 9HSC, highly suggestive changes of CJD, M = missing value.

Skinningsrud et al. Cerebrospinal Fluid Research 2008 5:14   doi:10.1186/1743-8454-5-14