Figure 2.

(A) Normalized band intensity of gelanolytic activity for CSF levels of MMP-2 (blue), MMP-9 (red), and 130 kDa MMP (green), and at baseline, after 6 weeks (1 cycle), and after 12 weeks (2 cycles) of treatment. Data are means +/- SEM, n = 4. (B) Representative zymography gel (light-dark reversed) of the CSF from Patient 1 showing stable gelanolytic activities from MMP-2 and 130 kDa MMP. But MMP-9 activity increased progressively over time.