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This article is part of the supplement: 51st Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida

Open AccessOral presentation

Does long term intravesical oxybutynin treatment of hyperreflexic neurogenic bladder result in bladder auto-augmentation?

Udo Rolle email, Christian Geyer, Thomas Lehnert, Margit Weißer and Holger Till

Department of Pediatric Surgery, University of Leipzig, Oststr. 21-25, 04317 Leipzig, Germany

author email corresponding author email

from 51st Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida
Heidelberg, Germany. 27–30 June 2007

Cerebrospinal Fluid Research 2007, 4(Suppl 1):S15doi:10.1186/1743-8454-4-S1-S15

Published: 20 December 2007

First paragraph (this article has no abstract)

The main goal of the treatment of neurogenic bladder is to promote continence and protect the upper urinary tract from deterioration. Conversion of a hyperreflexic detrusor to a lower pressure detrusor could be reached by the use of anticholinergic medication and clean intermittent catheterization (CIC). Important alternative to reduce side effects and lower the detrusor pressure is the intravesical administration of oxybutynin. The presented study investigated the urodynamic effects of the long-term administration of intravesical oxybutynin in hyperreflexic neurogenic bladder to evaluate the property of bladder auto-augmentation.


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