Mechanism of CSF outflow through human arachnoid granulations using in-vitro and ex-vivo perfusion models

doi:10.1186/1743-8454-3-S1-S11

Cerebrospinal Fluid Research

Volume 3
Suppl 1

Viewing options:

Abstract
Full text
PDF (149KB)

Related literature:

Articles citing this article
on Google Scholar
Other articles by authors
on Google Scholar

Holman DW
Grzybowski DM
Glimcher SA
Katz SE

on PubMed

Holman DW
Grzybowski DM
Glimcher SA
Katz SE
Related articles/pages
on Google

on Google Scholar

Tools:

Post to:

This article is part of the supplement: 50th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida .

Oral presentation

Mechanism of CSF outflow through human arachnoid granulations using in-vitro and ex-vivo perfusion models

David W Holman¹ , Deborah M Grzybowski¹^,2, Shelley A Glimcher¹ and Steven E Katz²

¹Biomedical Engineering Department, The Ohio State University, Columbus, OH 43210, USA

²Department of Ophthalmology, The Ohio State University, Columbus, OH 43210, USA

author email corresponding author email

from 50th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida
Cambridge, UK. 30 August – 2 September 2006

Cerebrospinal Fluid Research 2006, 3(Suppl 1):S11doi:10.1186/1743-8454-3-S1-S11


Published:	21 December 2006

First paragraph (this article has no abstract)

In communicating hydrocephalus and also idiopathic intracranial hypertension, disturbed CSF dynamics may result from an increased resistance to CSF outflow at the arachnoid granulations (AGs). To better understand the mechanism of CSF egress, we modeled the outflow of CSF through human AGs using both cell culture (in-vitro) and whole tissue (ex-vivo) perfusion models.