Table 1

Baseline characteristics of the seven AD-NPH subjects. The imaging studies were read by an independent neuroradiologist. The normal MDRS score is 142–144, the normal MMSE score is 27–30. Consequently, these patients are in the mild to moderate range of AD.

Subject number
1
2
3
4
5
6
7

Age
68
66
63
71
73
56
70
Gender
Male
Female
Female
Male
Male
Female
Male
Highest Education
<8th Grade
8th – 12th Grade
>12th Grade
>12th Grade
8th -12th Grade
8th – 12th Grade
8th – 12th Grade
Neurological History (other than AD)
None
None
None
None
None
Restless legs
Insomnia, headaches
Genitourinary History
Urinary Tract Infection, prostatitis
None
None
None
None
None
Overactive bladder, prostate hypertrophy
Abnormal Posture
Absent
Absent
Absent
Absent
Absent
Absent
Absent
Brain Image Type
MRI
MRI
MRI
CT
MRI
MRI
CT
Markedly Enlarged Ventricles?
No
No
No
No
No
No
No
Other Lesions on Brain Scan
None
Non-specific deep white matter changes
Small amt periventricular white matter changes
None
Mild changes noted on Flair image
None
None
Gait
Normal
Normal
Normal
Normal
Normal
Normal
Poor balance, unable to tandem gait, slow gait, no arm swinging
MDRS
111
123
127
120
120
118
109
MMSE
19
25
26
25
21
20
26
Opening pressure
240
235
260
260
250
220
280

Silverberg et al. Cerebrospinal Fluid Research 2006 3:7   doi:10.1186/1743-8454-3-7