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Epidemiology of neural tube defects and folic acid

David B Shurtleff email

Department of Pediatrics, University of Washington, Seattle, WA 98105, USA

author email corresponding author email

Cerebrospinal Fluid Research 2004, 1:5doi:10.1186/1743-8454-1-5

Published: 10 December 2004

Abstract

This review article combines four disparate observations about Neural Tube Defects (NTDs). They are the worldwide decline in the birth incidence that began prior to prenatal diagnosis; family recurrence risks; the effect of prenatal diagnosis and termination of affected pregnancies; and the effect of folic acid.


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